Milveterol hydrochloride

CAS No. 804518-03-4

Milveterol hydrochloride ( GSK 159797 hydrochloride )

Catalog No. M16012 CAS No. 804518-03-4

Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 288 Get Quote
10MG 423 Get Quote
25MG 695 Get Quote
50MG 972 Get Quote
100MG 1314 Get Quote
500MG 2628 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Milveterol hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity.
  • Description
    Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold); demonstrates high potency in vitro and long duration of action in a guinea pig model of bronchoprotection.Asthma Phase 2 Discontinued
  • Synonyms
    GSK 159797 hydrochloride
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    Adrenergic Receptor
  • Research Area
    Inflammation/Immunology
  • Indication
    Asthma

Chemical Information

  • CAS Number
    804518-03-4
  • Formula Weight
    471.98
  • Molecular Formula
    C25H30ClN3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1=CC=C(C=C1)C(CNC2=CC=C(C=C2)CCNCC(C3=CC(=C(C=C3)O)NC=O)O)O.Cl
  • Chemical Name
    N-(2-hydroxy-5-((R)-1-hydroxy-2-((4-(((R)-2-hydroxy-2-phenylethyl)amino)phenethyl)amino)ethyl)phenyl)formamide hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jacobsen JR, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1213-8.
2. Fuso L, et al. Curr Med Chem. 2013;20(12):1477-95.
3. Jacobsen JR, et al. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2625-30.
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